I started taking PolyC's about 13 months ago at about 204lbs a huge insulin belly (44 inch waist), high blood sugar, high cholesterol, on medication as I was pre diabetic, testosterone and estrogen imbalance and very irregular period. I was working out regularly but nothing was helping my symptoms and I wasn't loosing weight. Today I just hit 181lbs! I've gone from a size 18 to a size 14 and am no longer on any medications. My cycle is regular and I just feel so much better. I'm still taking my PolyC's regularly. Also working out and eating properly for my hormone type were other keys to my health change. Love these supplements, they have changed my life forever.